Sulfur metabolism
| PAG Title | Sulfur metabolism |
| PAG ID | WAG000199 |
| Type | P |
| Source Link |  KEGG |
| Publication Reference | NA |
| PAG Description | Sulfur is an essential element for life and the metabolism of organic sulfur compounds plays an important role in the global sulfur cycle. Sulfur occurs in various oxidation states ranging from +6 in sulfate to -2 in sulfide (H2S). Sulfate reduction can occur in both an energy consuming assimilatory pathway and an energy producing dissimilatory pathway. The assimilatory pathway, which is found in a wide range of organisms, produces reduced sulfur compounds for the biosynthesis of S-containing amino acids and does not lead to direct excretion of sulfide. In the dissimilatory pathway, which is restricted to obligatory aerobic bacterial and archaeal lineages, sulfate (or sulfur) is the termil electron acceptor of the respiratory chain producing large quantities of inorganic sulfide. Both pathways start from the activation of sulfate by reaction with ATP to form adenylyl sulfate (APS). In the assimilatory pathway [MD: |
| Species | Homo sapiens |
| nCoCo Score | 598 |
| Base PAG ID | WAG000199 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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